PTFE fiber and polyester fiber are one of the medical materials used for brain surgery and cardiovascular surgery, such as reinforcement of the suture part, prosthesis of the defect part after the excision. However there are many problems that these fibers did not adhere well to fibrin glue and tissue.

This study concerns fabrication of new cell adhesive materials by ion implantation into PTFE fiber and polyester fiber. PTFE fiber and polyester fiber were irradiated with 50, 150 keV and He⁺, Kr⁺ beams at fluences of 1*10¹⁴, 5*10¹⁴, and 1*10¹⁵ ions/cm². Surface characterization was studied using SEM, FT-IR-ATR, Raman spectroscopy. In vitro, L929 mouse fibroblast cells were cultured on ion-implanted specimen as a tissue compatibility test.

These results indicated that cell attachment to the ion-implanted fiber dramatically improved as compared with non-implanted fiber in PTFE fiber that irradiated with 150 keV and Kr⁺ beam at fluence of 1*10¹⁵ ions/cm² and polyester that irradiated with 150 keV and Kr⁺ beam at fluence of 5*10¹⁴ ions/cm² fiber. FT-IR-ATR study indicates that ion implantation destroyed the chemical structure the formation of a new C=C radical was observed. Raman spectroscopy study revealed that the C-C decomposed with increasing fluencies of irradiation in both Fibers. The peak that came from D band and G band was confirmed in the polyester fiber. With both ion-implanted fibers, C=C radical induced by ion-implantation ware major factor influencing cell invasion. It is therefore very likely that ion-implanted PTFE fiber and polyester fiber will be applicable for clinical use.

Shinya Morisaki*, Meiji University, Japan
Daisuke Mano, Meiji University, Japan
Atsushi Ogura, Meiji University, Japan
Toshiyuki Tanaka, RIKEN, Japan
Kyouichirou Mizutani, RIKEN, Japan
Yoshiaki Suzuki, RIKEN, Japan
Kazushi Sakuragi, RIKEN, Japan

*presenting author